Natural active ingredients of pharmaceutical interest
This topic groups together research aimed at the isolation, characterisation, quantitative analysis and evaluation of biological activity in in vitro and in vivo systems of natural active ingredients of pharmaceutical interest. In particular, extractive and chromatographic, spectroscopic (UV-Visible, NMR) and mass spectrometric techniques are used. In addition to the analytical aspect, the laboratory is equipped with molecular and cellular biology equipment for the evaluation of efficacy in cellular models.
- Della Vedova L., Gado F., Vieira T.A., Grandini, N.A., Palácio T.L.N., Siqueira J.S., Carini M., Bombardelli E., , Aldini G., Baron G. Chemical, Nutritional and Biological Evaluation of a Sustainable and Scalable Complex of Phytochemicals from Bergamot By-Products. Molecules 2023 Mar 26;28(7):2964. doi: 10.3390/molecules28072964.
- Della Vedova L., Ferrario G., Gado F., Altomare A., Carini M., Morazzoni P., Aldini G., Baron G. Liquid Chromatography–High-Resolution Mass Spectrometry (LC-HRMS) Profiling of Commercial Enocianina and Evaluation of Their Antioxidant and Anti-Inflammatory Activity. Antioxidants 2022 Jun 16;11(6):1187. doi: 10.3390/antiox11061187.
- Baron G, Altomare A, Mol M, Garcia JL, Correa C, Raucci A, Mancinelli L, Mazzotta S, Fumagalli L, Trunfio G, Tucci L, Lombardo E, Malara D, Janda E, Mollace V, Carini M, Bombardelli E, Aldini G. Analytical Profile and Antioxidant and Anti-Inflammatory Activities of the Enriched Polyphenol Fractions Isolated from Bergamot Fruit and Leave. Antioxidants 2021 Jan 20;10(2):141. doi: 10.3390/antiox10020141